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Myelin Basic Protein (DGR14508) Rabbit mAb (PBS Only)
db14893-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes. [provided by RefSeq, Jul 2008]
- Immunogen Recombinant protein of human Myelin Basic Protein
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Gene ID
4155
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Swiss Prot
P02686
- Synonyms MBP
- Reactivity Human
- Application WB, IHC-P
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Recommended dilution
WB: 1:2000-1:20000
IHC-P: 1:200-1:500 - Calculated MW 33 kDa
- Observed MW 18 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR14508
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/ml
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot detection of Myelin Basic Protein in Rat Brain lysates using db14893(1:1000 diluted).
订购信息
- Package Price (RMB)
- 100μg 5798
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
