您当前的位置：
MTH1 (DGR13753) Rabbit mAb (PBS Only)
db14894-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background Misincorporation of oxidized nucleoside triphosphates into DNA/RNA during replication and transcription can cause mutations that may result in carcinogenesis or neurodegeneration. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP, 8-oxo-dATP, 2-hydroxy-dATP, and 2-hydroxy rATP, to monophosphates, thereby preventing misincorporation. The encoded protein is localized mainly in the cytoplasm, with some in the mitochondria, suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. Several alternatively spliced transcript variants, some of which encode distinct isoforms, have been identified. Additional variants have been observed, but their full-length natures have not been determined. A single-nucleotide polymorphism that results in the production of an additional, longer isoform (p26) has been described. [provided by RefSeq, Jul 2008]
- Immunogen Recombinant protein of human MTH1
-
Gene ID
4521
-
Swiss Prot
P36639
- Synonyms MTH1
- Reactivity Human
- Application WB, IHC, ICC/IF, FC
-
Recommended dilution
WB: 1:1000
IHC: 1:20
ICC/IF: 1:50
FC: 1:20 - Calculated MW 23 kDa
- Observed MW 18 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR13753
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/ml
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
×
![]()
-
Western blot detection of MTH1 in K562 cell lysates using db14894(1:1000 diluted).
订购信息
- Package Price (RMB)
- 100μg 5798
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
