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Phospho-MEK4 (Ser80) (DGR33337) Rabbit mAb (PBS Only)
db14900-PBS
Datasheet

Product Name : Phospho-MEK4 (Ser80) (DGR33337) Rabbit mAb (PBS Only)

Cat.No.: db14900-PBS

Synonyms : JNKK; MEK4; MKK4; SEK1; SKK1; JNKK1; SERK1; MAPKK4; PRKMK4; SAPKK1; SAPKK-1

Application:

Reactivity : Human, Mouse

Host species : Rabbit

Conjugation/Formulation:PBS Only

  • Background This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
  • Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser80 of human MEK4/MKK4
  • Gene ID 6416
  • Swiss Prot P45985
  • Synonyms JNKK; MEK4; MKK4; SEK1; SKK1; JNKK1; SERK1; MAPKK4; PRKMK4; SAPKK1; SAPKK-1
  • Reactivity Human,Mouse
  • Application WB, IHC-P
  • Recommended dilution WB: 1:1000-1:5000
    IHC-P: 1:50-1:100
  • Calculated MW 44 kDa
  • Observed MW 44 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Clonality No. DGR33337
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Concentration 1 mg/ml
  • Formulation PBS Only
  • Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
  • Western blot analysis of extracts from 3T3 cells using db14900 at 1:1000.
  • Western blot analysis of extracts from A549, MCF-7, U251 cells using db14900 at 1:1000.
订购信息
  • Package Price (RMB)
  • 100μg 4498
  • 货期:现货
For research use only. Not intended for diagnostic.