VEGF Receptor 2 (DGR15717) Rabbit mAb (PBS Only)
Product Name :
VEGF Receptor 2 (DGR15717) Rabbit mAb (PBS Only)
Cat.No.:
db15008-PBS
Synonyms :
orv; Flk1; Ly73; Flk-1; Krd-1; VEGFR2; VEGFR-2; sVEGFR-2; 6130401C07
Reactivity :
Mouse, Rat
Host species :
Rabbit
Conjugation/Formulation：PBS Only
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Background
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain, such as isoform 2, may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. Isoform 2 plays an important role as a negative regulator of VEGFA- and VEGFC-mediated lymphangiogenesis by limiting the amount of free VEGFA and/or VEGFC and by preventing their binding to FLT4. Modulates FLT1 and FLT4 signaling by forming heterodimers.
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Immunogen
Recombinant protein of mouse VEGF Receptor 2
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Gene ID
16542
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Swiss Prot
P35918
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Synonyms
orv; Flk1; Ly73; Flk-1; Krd-1; VEGFR2; VEGFR-2; sVEGFR-2; 6130401C07
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Reactivity
Mouse,Rat
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Application
WB
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Recommended dilution
WB: 1:1000
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Calculated MW
153 kDa
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Observed MW
230,210 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR15717
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/ml
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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100μg
5798
- 货期：现货
For research use only. Not intended for diagnostic.
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