5HT2C Receptor (DGR15512) Rabbit mAb (PBS Only)
Product Name :
5HT2C Receptor (DGR15512) Rabbit mAb (PBS Only)
Cat.No.:
db15044-PBS
Synonyms :
HTR1C; 5-HT1C; 5-HT2C; 5HTR2C; 5-HTR2C
Reactivity :
Human
Host species :
Rabbit
Conjugation/Formulation:PBS Only
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Background
This gene encodes a seven-transmembrane G-protein-coupled receptor. The encoded protein responds to signaling through the neurotransmitter serotonin. The mRNA of this gene is subject to multiple RNA editing events, where adenosine residues encoded by the genome are converted to inosines. RNA editing is predicted to alter the structure of the second intracellular loop, thereby generating alternate protein forms with decreased ability to interact with G proteins. Abnormalities in RNA editing of this gene have been detected in victims of suicide that suffer from depression. In addition, naturally-occuring variation in the promoter and 5' non-coding and coding regions of this gene may show statistically-significant association with mental illness and behavioral disorders. Alternative splicing results in multiple different transcript variants. [provided by RefSeq, Jan 2015]
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Immunogen
A synthetic peptide of human 5HT2C Receptor
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Gene ID
3358
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Swiss Prot
P28335
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Synonyms
HTR1C; 5-HT1C; 5-HT2C; 5HTR2C; 5-HTR2C
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Reactivity
Human
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Application
WB
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Calculated MW
52 kDa
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Observed MW
52 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR15512
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/mL
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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100μg
4498
- 货期:现货
For research use only. Not intended for diagnostic.