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Galectin-9 (DGR15153) Rabbit mAb

Product Name : Galectin-9 (DGR15153) Rabbit mAb

Cat.No.: db15129

Synonyms : gal-9; Lgals5; LGALS35; AA407335; AI194909; AI265545; galectin-9

Application:

Reactivity : Mouse

Host species : Rabbit

Conjugation/Formulation:Un-conjugated

  • Background Binds galactosides (By similarity). Has high affinity for the Forssman pentasaccharide (By similarity). Ligand for HAVCR2/TIM3 (By similarity). Binding to HAVCR2 induces T-helper type 1 lymphocyte (Th1) death (By similarity). Also stimulates bactericidal activity in infected macrophages by causing macrophage activation and IL1B secretion which restricts intracellular bacterial growth (PubMed:20937702). Ligand for P4HB; the interaction retains P4HB at the cell surface of Th2 T-helper cells, increasing disulfide reductase activity at the plasma membrane, altering the plasma membrane redox state and enhancing cell migration (PubMed:21670307). Ligand for CD44; the interaction enhances binding of SMAD3 to the FOXP3 promoter, leading to up-regulation of FOXP3 expression and increased induced regulatory T (iTreg) cell stability and suppressive function (PubMed:25065622).
  • Immunogen Recombinant protein of mouse Galectin-9
  • Gene ID 16859
  • Swiss Prot O08573
  • Synonyms gal-9; Lgals5; LGALS35; AA407335; AI194909; AI265545; galectin-9
  • Reactivity Mouse
  • Application WB
  • Recommended dilution WB: 1:1000
  • Calculated MW 40 kDa
  • Observed MW 40 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Clonality No. DGR15153
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
  • Western blot analysis of extracts from Mouse lung tissue using db15129 at 1:1000.
订购信息
  • Package Price (RMB)
  • 10μL 398
  • 20μL 698
  • 50μL 1398
  • 100μL 2398
  • 货期:现货
For research use only. Not intended for diagnostic.