Galectin-9 (DGR15153) Rabbit mAb
Product Name :
Galectin-9 (DGR15153) Rabbit mAb
Cat.No.:
db15129
Synonyms :
gal-9; Lgals5; LGALS35; AA407335; AI194909; AI265545; galectin-9
Reactivity :
Mouse
Host species :
Rabbit
Conjugation/Formulation:Un-conjugated
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Background
Binds galactosides (By similarity). Has high affinity for the Forssman pentasaccharide (By similarity). Ligand for HAVCR2/TIM3 (By similarity). Binding to HAVCR2 induces T-helper type 1 lymphocyte (Th1) death (By similarity). Also stimulates bactericidal activity in infected macrophages by causing macrophage activation and IL1B secretion which restricts intracellular bacterial growth (PubMed:20937702). Ligand for P4HB; the interaction retains P4HB at the cell surface of Th2 T-helper cells, increasing disulfide reductase activity at the plasma membrane, altering the plasma membrane redox state and enhancing cell migration (PubMed:21670307). Ligand for CD44; the interaction enhances binding of SMAD3 to the FOXP3 promoter, leading to up-regulation of FOXP3 expression and increased induced regulatory T (iTreg) cell stability and suppressive function (PubMed:25065622).
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Immunogen
Recombinant protein of mouse Galectin-9
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Gene ID
16859
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Swiss Prot
O08573
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Synonyms
gal-9; Lgals5; LGALS35; AA407335; AI194909; AI265545; galectin-9
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Reactivity
Mouse
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Application
WB
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Recommended dilution
WB: 1:1000
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Calculated MW
40 kDa
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Observed MW
40 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR15153
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
×
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Western blot analysis of extracts from Mouse lung tissue using db15129 at 1:1000.
订购信息
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Package
Price (RMB)
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10μL
398
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20μL
698
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50μL
1398
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100μL
2398
- 货期:现货
For research use only. Not intended for diagnostic.