CLDN18.2 (DGR15119) Rabbit mAb (PBS Only)
Product Name :
CLDN18.2 (DGR15119) Rabbit mAb (PBS Only)
Cat.No.:
db15136-PBS
Synonyms :
SFTA5; SFTPJ; Claudin 18.2; Claudin-18.2
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
Conjugation/Formulation：PBS Only
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Background
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2010]
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Immunogen
A synthetic peptide of human CLDN18.2
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Gene ID
51208
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Swiss Prot
P56856-2
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Synonyms
SFTA5; SFTPJ; Claudin 18.2; Claudin-18.2
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Reactivity
Human,Mouse,Rat
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Application
IHC-P
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Recommended dilution
IHC-P: 1:200-1:500
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Calculated MW
28 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR15119
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/ml
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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100μg
5798
- 货期：现货
For research use only. Not intended for diagnostic.
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