Granulin (DGR15099) Rabbit mAb
Product Name :
Granulin (DGR15099) Rabbit mAb
Cat.No.:
db15145
Synonyms :
GEP; GP88; PEPI; PGRN; CLN11; PCDGF
Reactivity :
Human
Host species :
Rabbit
Conjugation/Formulation：Un-conjugated
-
Background
Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis. [provided by RefSeq, Jul 2008]
-
Immunogen
A synthetic peptide of human Granulin
-
Gene ID
2896
-
Swiss Prot
P28799
-
Synonyms
GEP; GP88; PEPI; PGRN; CLN11; PCDGF
-
Reactivity
Human
-
Application
WB, IHC-P, ICC/IF, FC, IP
-
Recommended dilution
WB: 1:1000-1:5000
IHC-P: 1:100-1:200
ICC/IF: 1:100-1:200
FC: 1:200
IP: 1:10-1:100
-
Calculated MW
64 kDa
-
Observed MW
55,88 kDa
-
Host species
Rabbit
-
Clonality
Monoclonal
-
Clonality No.
DGR15099
-
Isotype
IgG
-
Purity
Affinity Purification
-
Conjugation
Un-conjugated
-
Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
-
Package
Price (RMB)
-
10μL
398
-
20μL
698
-
50μL
1398
-
100μL
2398
- 货期：现货
For research use only. Not intended for diagnostic.
浙公网安备 33010602008812号