CD41 (DGR15089) Rabbit mAb (PBS Only)
Product Name :
CD41 (DGR15089) Rabbit mAb (PBS Only)
Cat.No.:
db15146-PBS
Synonyms :
CD41; CD41B; GpIIb; AI172977; alphaIIb
Reactivity :
Mouse, Rat
Host species :
Rabbit
Conjugation/Formulation:PBS Only
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Background
Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
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Immunogen
Recombinant protein of mouse CD41
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Gene ID
16399
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Swiss Prot
Q9QUM0
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Synonyms
CD41; CD41B; GpIIb; AI172977; alphaIIb
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Reactivity
Mouse,Rat
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Application
WB, IHC-P
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Recommended dilution
WB: 1:1000
IHC-P: 1:200-1:500
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Calculated MW
113 kDa
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Observed MW
113 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR15089
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/ml
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
×
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Western blot analysis of extracts from Mouse spleen tissue using
db15146
订购信息
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Package
Price (RMB)
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100μg
5798
- 货期:现货
For research use only. Not intended for diagnostic.