Nephrin (DGR15066) Rabbit mAb (PBS Only)
Product Name :
Nephrin (DGR15066) Rabbit mAb (PBS Only)
Cat.No.:
db15156-PBS
Synonyms :
CNF; NPHN; nephrin
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
Conjugation/Formulation:PBS Only
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Background
This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.[provided by RefSeq, Oct 2009]
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Immunogen
A synthetic peptide of human Nephrin
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Gene ID
4868
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Swiss Prot
O60500
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Synonyms
CNF; NPHN; nephrin
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Reactivity
Human,Mouse,Rat
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Application
WB, IHC-P, IP
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Recommended dilution
WB: 1:1000
IHC-P: 1:200-1:1000
IP: 1:20-1:50
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Calculated MW
135 kDa
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Observed MW
200 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR15066
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/ml
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
×
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Western blot analysis of extracts from Mouse kidney tissue using
db15156
订购信息
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Package
Price (RMB)
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100μg
5798
- 货期:现货
For research use only. Not intended for diagnostic.