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Product Name : MICA (DGR14965) Rabbit mAb
Cat.No.: db15182
Synonyms : MIC-A; PERB11.1
Application：
Reactivity : Human
Host species : Rabbit
Conjugation/Formulation：Un-conjugated
- Background This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2014]
- Immunogen A synthetic peptide of human MICA
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Gene ID
100507436
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Swiss Prot
Q29983
- Synonyms MIC-A; PERB11.1
- Reactivity Human
- Application WB
- Recommended dilution WB: 1:1000-1:5000
- Calculated MW 43 kDa
- Observed MW 43-70 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR14965
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from HeLa cells using db15182 at 1:1000.
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
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For research use only. Not intended for diagnostic.
