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5 Lipoxygenase (DGR14745) Rabbit mAb (PBS Only)
db15240-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
- Immunogen A synthetic peptide of human 5 Lipoxygenase
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Gene ID
240
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Swiss Prot
P09917
- Synonyms 5-LO; 5LPG; LOG5; 5-LOX
- Reactivity Human,Rat
- Application WB, IHC-P, ICC/IF, FC
- Calculated MW 78 kDa
- Observed MW 78 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR14745
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/ml
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from K562 cells using db15240
订购信息
- Package Price (RMB)
- 100μg 4498
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
