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CD45 (DGR14623) Rabbit mAb (PBS Only)
db15259-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]
- Immunogen A synthetic peptide of mouse CD45
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Gene ID
5788
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Swiss Prot
P06800
- Synonyms LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180
- Reactivity Human,Mouse
- Application WB, IHC-P, IP
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Recommended dilution
WB: 1:1000
IHC-P: 1:1000-1:5000
IP: 1:20-1:50 - Calculated MW 147 kDa
- Observed MW 180-240 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR14623
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/ml
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from Jurkat cells using db15259
订购信息
- Package Price (RMB)
- 100μg 4498
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
