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Conjugation/Formulation：Un-conjugated
- Background The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2013]
- Immunogen Recombinant protein of human Uromucoid
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Gene ID
7369
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Swiss Prot
P07911
- Synonyms THP; FJHN; HNFJ; THGP; HNFJ1; MCKD2; ADMCKD2
- Reactivity Human
- Application WB, IHC-P
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Recommended dilution
WB: 1:1000
IHC-P: 1:500-1:2000 - Calculated MW 70 kDa
- Observed MW 115 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR14551
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from Human urine tissue using db15270 at 1:5000.
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
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For research use only. Not intended for diagnostic.
