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CD31 (DGR14420) Rabbit mAb (PBS Only)
db15306-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-679 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Prevents phagocyte ingestion of closely apposed viable cells by transmitting 'detachment' signals, and changes function on apoptosis, promoting tethering of dying cells to phagocytes (the encounter of a viable cell with a phagocyte via the homophilic interaction of PECAM1 on both cell surfaces leads to the viable cell's active repulsion from the phagocyte. During apoptosis, the inside-out signaling of PECAM1 is somehow disabled so that the apoptotic cell does not actively reject the phagocyte anymore.
- Immunogen Recombinant protein of mouse CD31
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Gene ID
18613
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Swiss Prot
Q08481
- Synonyms Cd31; Pecam; C85791; PECAM-1
- Reactivity Mouse,Rat
- Application WB, ICC/IF, IHC-P
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Recommended dilution
WB: 1:1000
ICC/IF: 1:100
IHC-P: 1:100-1:200 - Calculated MW 83 kDa
- Observed MW 130-135 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR14420
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/ml
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from Mouse lung tissue using db15306
订购信息
- Package Price (RMB)
- 100μg 5798
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
