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Hsp105 (DGR14032) Rabbit mAb (PBS Only)
db15453-PBS
Datasheet

Product Name : Hsp105 (DGR14032) Rabbit mAb (PBS Only)

Cat.No.: db15453-PBS

Synonyms : HSP105; HSP105A; HSP105B; NY-CO-25

Application:

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Conjugation/Formulation:PBS Only

  • Background This gene encodes a member of the heat shock protein 70 family of proteins. The encoded protein functions as a nucleotide exchange factor for the molecular chaperone heat shock cognate 71 kDa protein (Hsc70). In addition, this protein plays a distinct but related role as a holdase that inhibits the aggregation of misfolded proteins, including the cystic fibrosis transmembrane conductance regulator (CFTR) protein. Elevated expression of this protein has been observed in numerous human cancers. [provided by RefSeq, Mar 2017]
  • Immunogen A synthetic peptide of human Hsp105
  • Gene ID 10808
  • Swiss Prot Q92598
  • Synonyms HSP105; HSP105A; HSP105B; NY-CO-25
  • Reactivity Human,Mouse,Rat
  • Application WB, IHC-P, ICC/IF, IP
  • Calculated MW 97 kDa
  • Observed MW 105 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Clonality No. DGR14032
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Concentration 1 mg/mL
  • Formulation PBS Only
  • Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
  • Western blot analysis of extracts from MCF-7 cells using db15453 at 1:1000.
  • Immunofluorescence analysis of HeLa cells labelling Hsp105 with db15453.

    The cells were fixed with cold 100% methanol (10min, 4℃) and blocked in 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween 20 for 1h. The cells were then incubate with db15453 (1:100) at room temprature for 1h, followed by a further incubation at room temperature for 45min with Goat Anti Rabbit lgG (H+L)-AF488 db10005, shown in green). Nuclear DNA was labeled in blue with DAPI.

    Control: Secondary antibody only.
订购信息
  • Package Price (RMB)
  • 10μg 1898
  • 100μg 5798
  • 货期:现货
For research use only. Not intended for diagnostic.