Urm1 (DGR13592) Rabbit mAb (PBS Only)
Product Name :
Urm1 (DGR13592) Rabbit mAb (PBS Only)
Cat.No.:
db15535-PBS
Synonyms :
C9orf74
Reactivity :
Human
Host species :
Rabbit
Conjugation/Formulation：PBS Only
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Background
Acts as a sulfur carrier required for 2-thiolation of mcm5S2U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm5S2U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as MOCS3, ATPBD3, CTU2, USP15 and CAS. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
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Immunogen
A synthetic peptide of human Urm1
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Gene ID
81605
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Swiss Prot
Q9BTM9
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Synonyms
C9orf74
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Reactivity
Human
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Application
WB
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Calculated MW
11 kDa
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Observed MW
11 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR13592
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/mL
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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10μg
1498
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100μg
4498
- 货期：现货
For research use only. Not intended for diagnostic.
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