ZAP70单克隆抗体(DGR12683) | 高特异性&高亲和力

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Recombinant DGRmAb^®

ZAP70 (DGR12683) Rabbit mAb (PBS Only)

db15743-PBS

Datasheet

Product Name : ZAP70 (DGR12683) Rabbit mAb (PBS Only)

Cat.No.: db15743-PBS

Synonyms : SRK; STD; TZK; STCD; IMD48; ADMIO2; ZAP-70

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated PBS Only

Background This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human ZAP70
Gene ID 7535
Swiss Prot P43403
Synonyms SRK; STD; TZK; STCD; IMD48; ADMIO2; ZAP-70
Reactivity Human
Application WB, ICC/IF, FC, IP
Recommended dilution WB: 1:1000
ICC/IF: 1:20-1:50
FC: 1:20
IP: 1:20
Calculated MW 70 kDa
Observed MW 70 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR12683
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Concentration 1 mg/ml
Formulation PBS Only
Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.

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