Dnmt3b单克隆抗体(DGR12594) | 高特异性&高亲和力

产品中心 Products Center

您当前的位置：

Recombinant DGRmAb^®

Dnmt3b (DGR12594) Rabbit mAb (PBS Only)

db15761-PBS

Datasheet

Product Name : Dnmt3b (DGR12594) Rabbit mAb (PBS Only)

Cat.No.: db15761-PBS

Synonyms : ICF; ICF1; M.HsaIIIB

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated PBS Only

Background CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined. [provided by RefSeq, May 2011]
Immunogen A synthetic peptide of human Dnmt3b
Gene ID 1789
Swiss Prot Q9UBC3
Synonyms ICF; ICF1; M.HsaIIIB
Reactivity Human,Mouse,Rat
Application WB
Calculated MW 96 kDa
Observed MW 96 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR12594
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Concentration 1 mg/mL
Formulation PBS Only
Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.

订购信息