CD162单克隆抗体(DGR11570) | 高特异性&高亲和力

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Recombinant DGRmAb^®

CD162 (DGR11570) Rabbit mAb (PBS Only)

db15963-PBS

Datasheet

Product Name : CD162 (DGR11570) Rabbit mAb (PBS Only)

Cat.No.: db15963-PBS

Synonyms : CLA; CD162; PSGL1; PSGL-1

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated PBS Only

Background This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011]
Immunogen A synthetic peptide of human CD162
Gene ID 6404
Swiss Prot Q14242
Synonyms CLA; CD162; PSGL1; PSGL-1
Reactivity Human
Application WB
Recommended dilution WB: 1:1000
Calculated MW 43 kDa
Observed MW 110 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR11570
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Concentration 1 mg/ml
Formulation PBS Only
Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.

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