Hepcidin-25单克隆抗体(DGR11561) | 高特异性&高亲和力

产品中心 Products Center

您当前的位置：

Recombinant DGRmAb^®

Hepcidin-25 (DGR11561) Rabbit mAb

db15965

年底大促

Datasheet

Product Name : Hepcidin-25 (DGR11561) Rabbit mAb

Cat.No.: db15965

Synonyms : HEPC; PLTR; HFE2B; LEAP1

Application：

Reactivity : Human, Rat

Host species : Rabbit

Un-conjugated

Background The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity against bacteria and fungi. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq, Oct 2014]
Immunogen Recombinant protein of human Hepcidin-25
Gene ID 57817
Swiss Prot P81172
Synonyms HEPC; PLTR; HFE2B; LEAP1
Reactivity Human,Rat
Application WB
Recommended dilution WB: 1:1000
Calculated MW 9 kDa
Observed MW 9,3 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR11561
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

订购信息