NFkB p100 (DGR11547) Rabbit mAb (PBS Only)
Product Name :
NFkB p100 (DGR11547) Rabbit mAb (PBS Only)
Cat.No.:
db15969-PBS
Synonyms :
p52; p100; H2TF1; LYT10; CVID10; LYT-10; NF-kB2; p49/p100
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
Conjugation/Formulation:PBS Only
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Background
This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
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Immunogen
Recombinant protein of human NFkB p100
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Gene ID
4791
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Swiss Prot
Q00653
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Synonyms
p52; p100; H2TF1; LYT10; CVID10; LYT-10; NF-kB2; p49/p100
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Reactivity
Human,Mouse,Rat
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Application
WB, ICC/IF, FC, IP
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Recommended dilution
WB: 1:1000
ICC/IF: 1:100-1:200
FC: 1:50-1:100
IP: 1:20
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Calculated MW
97 kDa
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Observed MW
120 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR11547
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/ml
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
×
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Western blot analysis of extracts from HeLa, MCF-7 cells using
db15969
订购信息
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Package
Price (RMB)
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100μg
5798
- 货期:现货
For research use only. Not intended for diagnostic.