RNF8 (DGR35988) Rabbit mAb - diagbio | 戴格生物

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Recombinant DGRmAb^®

RNF8 (DGR35988) Rabbit mAb

db16210

Datasheet

Product Name : RNF8 (DGR35988) Rabbit mAb

Cat.No.: db16210

Synonyms : hRNF8; KIAA0646; RING finger protein 8; E3 ubiquitin-protein ligase RNF8

Application：

Reactivity : Human, Rat

Host species : Rabbit

Un-conjugated

Background The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
Immunogen A synthetic peptide of Human RNF8
Gene ID 9025
Swiss Prot O76064
Synonyms hRNF8; KIAA0646; RING finger protein 8; E3 ubiquitin-protein ligase RNF8
Reactivity Human, Rat
Application WB
Recommended dilution WB: 1:1000-1:5000
Calculated MW 56 kDa
Observed MW 65 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR35988
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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