ACVR2A (DGR36031) Rabbit mAb - diagbio | 戴格生物

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Recombinant DGRmAb^®

ACVR2A (DGR36031) Rabbit mAb

db16266

Datasheet

Product Name : ACVR2A (DGR36031) Rabbit mAb

Cat.No.: db16266

Synonyms : ACVR2; ACTRII

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated

Background This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jun 2013]
Immunogen A synthetic peptide of Human ACVR2A
Gene ID 92
Swiss Prot P27037
Synonyms ACVR2; ACTRII
Reactivity Human, Mouse, Rat
Application WB
Recommended dilution WB: 1:1000
Calculated MW 58 kDa
Observed MW 80 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR36031
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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