Caspase-5 (DGR36049) Rabbit mAb - diagbio | 戴格生物

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Recombinant DGRmAb^®

Caspase-5 (DGR36049) Rabbit mAb

db16284

Datasheet

Product Name : Caspase-5 (DGR36049) Rabbit mAb

Cat.No.: db16284

Synonyms : ICH-3; ICEREL-III; ICE(rel)III

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated

Background This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Aug 2010]
Immunogen A synthetic peptide of Human Caspase-5
Gene ID 838
Swiss Prot P51878
Synonyms ICH-3; ICEREL-III; ICE(rel)III
Reactivity Human, Mouse, Rat
Application WB, IHC-P, IP
Recommended dilution WB: 1:1000-1:5000
IHC-P: 1:100
IP: 1:50
Calculated MW 50 kDa
Observed MW 50 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR36049
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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