CHM (DGR36067) Rabbit mAb - diagbio | 戴格生物

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Recombinant DGRmAb^®

CHM (DGR36067) Rabbit mAb

db16302

Datasheet

Product Name : CHM (DGR36067) Rabbit mAb

Cat.No.: db16302

Synonyms : TCD; GGTA; REP-1; DXS540; HSD-32

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated

Background This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia; also known as tapetochoroidal dystrophy (TCD). This X-linked disease is characterized by progressive dystrophy of the choroid, retinal pigment epithelium and retina. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016]
Immunogen A synthetic peptide of Human CHM
Gene ID 1121
Swiss Prot P24386
Synonyms TCD; GGTA; REP-1; DXS540; HSD-32
Reactivity Human, Mouse, Rat
Application WB, ICC/IF
Recommended dilution WB: 1:1000
ICC/IF: 1:200-1:500
Calculated MW 74 kDa
Observed MW 95 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR36067
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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