COASY (DGR36070) Rabbit mAb - diagbio | 戴格生物

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Recombinant DGRmAb^®

COASY (DGR36070) Rabbit mAb

db16305

Datasheet

Product Name : COASY (DGR36070) Rabbit mAb

Cat.No.: db16305

Synonyms : NBP; DPCK; PPAT; UKR1; NBIA6; PCH12; pOV-2

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated

Background Coenzyme A (CoA) functions as a carrier of acetyl and acyl groups in cells and thus plays an important role in numerous synthetic and degradative metabolic pathways in all organisms. In eukaryotes, CoA and its derivatives are also involved in membrane trafficking and signal transduction. This gene encodes the bifunctional protein coenzyme A synthase (CoAsy) which carries out the last two steps in the biosynthesis of CoA from pantothenic acid (vitamin B5). The phosphopantetheine adenylyltransferase domain of this bifunctional protein catalyzes the conversion of 4'-phosphopantetheine into dephospho-coenzyme A (dpCoA) while its dephospho-CoA kinase domain completes the final step by phosphorylating dpCoA to form CoA. Mutations in this gene are associated with neurodegeneration with brain iron accumulation (NBIA). Alternative splicing results in multiple isoforms. [provided by RefSeq, Apr 2014]
Immunogen A synthetic peptide of Human COASY
Gene ID 80347
Swiss Prot Q13057
Synonyms NBP; DPCK; PPAT; UKR1; NBIA6; PCH12; pOV-2
Reactivity Human
Application WB, FC
Recommended dilution WB: 1:1000-1:5000
FC: 1:50-1:200
Calculated MW 62 kDa
Observed MW 62 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR36070
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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