CSK (DGR36076) Rabbit mAb - diagbio | 戴格生物

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Recombinant DGRmAb^®

CSK (DGR36076) Rabbit mAb

db16311

Datasheet

Product Name : CSK (DGR36076) Rabbit mAb

Cat.No.: db16311

Synonyms : C-Src kinase; Protein-tyrosine kinase CYL; Tyrosine-protein kinase CSK

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated

Background The protein encoded by this gene is involved in multiple pathways, including the regulation of Src family kinases. It plays an important role in T-cell activation through its association with the protein encoded by the protein tyrosine phosphatase, non-receptor type 22 (PTPN22) gene. This protein also phosphorylates C-terminal tyrosine residues on multiple substrates, including the protein encoded by the SRC proto-oncogene, non-receptor tyrosine kinase gene. Phosphorylation suppresses the kinase activity of the Src family tyrosine kinases. An intronic polymorphism (rs34933034) in this gene has been found to affect B-cell activation and is associated with systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017]
Immunogen A synthetic peptide of Human CSK
Gene ID 1445
Swiss Prot P41240
Synonyms C-Src kinase; Protein-tyrosine kinase CYL; Tyrosine-protein kinase CSK
Reactivity Human, Mouse, Rat
Application WB, IHC-P
Recommended dilution WB: 1:1000
IHC-P: 1:100-1:200
Calculated MW 51 kDa
Observed MW 50 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR36076
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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