CXCR6 (DGR36078) Rabbit mAb
Product Name :
CXCR6 (DGR36078) Rabbit mAb
Cat.No.:
db16313
Synonyms :
BONZO; CD186; CDw186; STRL33; TYMSTR
Reactivity :
Human
Host species :
Rabbit
Conjugation/Formulation：Un-conjugated
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Background
The protein encoded by this gene is a G protein-coupled receptor with seven transmembrane domains that belongs to the CXC chemokine receptor family. This family also includes CXCR1, CXCR2, CXCR3, CXCR4, CXCR5, and CXCR7. This gene, which maps to the chemokine receptor gene cluster, is expressed in several T lymphocyte subsets and bone marrow stromal cells. The encoded protein and its exclusive ligand, chemokine ligand 16 (CCL16), are part of a signalling pathway that regulates T lymphocyte migration to various peripheral tissues (the liver, spleen red pulp, intestine, lungs, and skin) and promotes cell-cell interaction with dendritic cells and fibroblastic reticular cells. CXCR6/CCL16 also controls the localization of resident memory T lymphocytes to different compartments of the lung and maintains airway resident memory T lymphocytes, which are an important first line of defense against respiratory pathogens. The encoded protein serves as an entry coreceptor used by HIV-1 and SIV to enter target cells, in conjunction with CD4. [provided by RefSeq, Aug 2020]
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Immunogen
A synthetic peptide of Human CXCR6
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Gene ID
10663
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Swiss Prot
O00574
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Synonyms
BONZO; CD186; CDw186; STRL33; TYMSTR
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Reactivity
Human
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Application
WB
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Recommended dilution
WB: 1:1000-1:5000
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Calculated MW
39 kDa
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Observed MW
39 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR36078
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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10μL
398
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20μL
698
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50μL
1398
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100μL
2398
- 货期：1-2 周
For research use only. Not intended for diagnostic.
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