DSC1 (DGR36087) Rabbit mAb - diagbio | 戴格生物

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Recombinant DGRmAb^®

DSC1 (DGR36087) Rabbit mAb

db16322

Datasheet

Product Name : DSC1 (DGR36087) Rabbit mAb

Cat.No.: db16322

Synonyms : CDHF1; DG2/DG3

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated

Background The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. A subtype of IgA pemphigus, a life-threatening autoimmune disease, is characterized by the presence of autoantibodies that target the encoded protein. The desmosomal family members are arranged in two clusters on chromosome 18. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protein. [provided by RefSeq, Nov 2015]
Immunogen A synthetic peptide of Human DSC1
Gene ID 1823
Swiss Prot Q08554
Synonyms CDHF1; DG2/DG3
Reactivity Human, Mouse, Rat
Application WB
Recommended dilution WB: 1:1000-1:5000
Calculated MW 100 kDa
Observed MW 100 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR36087
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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