GPX2 (DGR36117) Rabbit mAb (PBS Only)
Product Name :
GPX2 (DGR36117) Rabbit mAb (PBS Only)
Cat.No.:
db16352-PBS
Synonyms :
GPRP; GPx-2; GI-GPx; GPRP-2; GPx-GI; GSHPx-2; GSHPX-GI
Reactivity :
Human
Host species :
Rabbit
Conjugation/Formulation：PBS Only
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Background
The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is predominantly expressed in the gastrointestinal tract (also in liver in human), is localized in the cytoplasm, and whose preferred substrate is hydrogen peroxide. Overexpression of this gene is associated with increased differentiation and proliferation in colorectal cancer. This isozyme is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2016]
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Immunogen
A synthetic peptide of human GPX2
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Gene ID
2877
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Swiss Prot
P18283
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Synonyms
GPRP; GPx-2; GI-GPx; GPRP-2; GPx-GI; GSHPx-2; GSHPX-GI
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Reactivity
Human
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Application
WB, IHC-P
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Recommended dilution
WB: 1:1000-1:5000
IHC-P: 1:100-1:200
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Calculated MW
22 kDa
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Observed MW
22 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR36117
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/ml
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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100μg
4498
- 货期：现货
For research use only. Not intended for diagnostic.
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