ILF2 (DGR36143) Rabbit mAb - diagbio | 戴格生物

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Recombinant DGRmAb^®

ILF2 (DGR36143) Rabbit mAb

db16378

Datasheet

Product Name : ILF2 (DGR36143) Rabbit mAb

Cat.No.: db16378

Synonyms : NF45; PRO3063

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated

Background The protein encoded by this gene is a transcription factor required for T-cell expression of the interleukin 2 gene. It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. The encoded 45 kDa protein (NF45, ILF2) forms a complex with the 90 kDa interleukin enhancer-binding factor 3 (NF90, ILF3), and this complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm, to repair DNA breaks by nonhomologous end joining, and to negatively regulate the microRNA processing pathway. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. Alternative splicing results in multiple transcript variants. Related pseudogenes have been found on chromosomes 3 and 14. [provided by RefSeq, Dec 2014]
Immunogen A synthetic peptide of Human ILF2
Gene ID 3608
Swiss Prot Q12905
Synonyms NF45; PRO3063
Reactivity Human, Mouse, Rat
Application WB, IHC-P, FC, IP
Recommended dilution WB: 1:1000
IHC-P: 1:100-1:200
FC: 1:200-1:1000
IP: 1:50-1:100
Calculated MW 43 kDa
Observed MW 43 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR36143
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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