LFNG (DGR36157) Rabbit mAb - diagbio | 戴格生物

产品中心 Products Center

您当前的位置：

Recombinant DGRmAb^®

LFNG (DGR36157) Rabbit mAb

db16392

Datasheet

Product Name : LFNG (DGR36157) Rabbit mAb

Cat.No.: db16392

Synonyms : SCDO3

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated

Background This gene is a member of the glycosyltransferase 31 gene family. Members of this gene family, which also includes the MFNG (GeneID: 4242) and RFNG (GeneID: 5986) genes, encode evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, these proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. The protein encoded by this gene is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150). Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3. [provided by RefSeq, May 2018]
Immunogen A synthetic peptide of Human LFNG
Gene ID 3955
Swiss Prot Q8NES3
Synonyms SCDO3
Reactivity Human, Mouse, Rat
Application WB, FC
Recommended dilution WB: 1:1000-1:10000
FC: 1:00-1:1000
Calculated MW 42 kDa
Observed MW 44 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR36157
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

订购信息