Phospho-Pyrin (Ser241) (DGR14134) Rabbit mAb - diagbio | 戴格生物

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Recombinant DGRmAb^®

Phospho-Pyrin (Ser241) (DGR14134) Rabbit mAb

db16673

年底大促

Datasheet

Product Name : Phospho-Pyrin (Ser241) (DGR14134) Rabbit mAb

Cat.No.: db16673

Synonyms : FMF; pyrin; TRIM20

Application：

Reactivity : Mouse

Host species : Rabbit

Un-conjugated PBS Only

Background Predicted to enable actin binding activity; identical protein binding activity; and ubiquitin protein ligase activity. Involved in positive regulation of inflammatory response and positive regulation of interleukin-1 beta production. Predicted to be located in nucleus. Predicted to be part of canonical inflammasome complex and microtubule associated complex. Predicted to be active in cytosol and nucleoplasm. Is expressed in bladder; central nervous system; female associated reproductive structure; ureter; and urethra of female. Used to study familial Mediterranean fever. Human ortholog(s) of this gene implicated in several diseases, including IgA vasculitis; Sweet syndrome; asthma; familial Mediterranean fever; and hematologic cancer (multiple). Orthologous to human MEFV (MEFV innate immunity regulator, pyrin). [provided by Alliance of Genome Resources, Apr 2025]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser241 of mouse Pyrin
Gene ID 54483
Swiss Prot Q9JJ26
Synonyms FMF; pyrin; TRIM20
Reactivity Mouse
Application WB
Recommended dilution WB: 1:1000
Calculated MW 86 kDa
Observed MW 110 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR14134
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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