Phospho-Integrin alpha 4 (Ser1027) Rabbit pAb - diagbio | 戴格生物

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Phospho-Integrin alpha 4 (Ser1027) Rabbit pAb

db1776

年底大促

Datasheet

Product Name : Phospho-Integrin alpha 4 (Ser1027) Rabbit pAb

Cat.No.: db1776

Synonyms : IA4; CD49D

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated

Background The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser1027 of human Integrin alpha 4
Gene ID 3676
Swiss Prot P13612
Synonyms IA4; CD49D
Reactivity Human, Mouse, Rat
Application WB
Recommended dilution WB: 1:1000
Calculated MW 115 kDa
Observed MW 150,70 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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