FGR Rabbit pAb - diagbio | 戴格生物

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FGR Rabbit pAb

db1832

Datasheet

Product Name : FGR Rabbit pAb

Cat.No.: db1832

Synonyms : SRC2; c-fgr; c-src2; p55-Fgr; p58-Fgr; p55c-fgr; p58c-fgr

Application : WB, ICC/IF

Reactivity : Human

Host species : Rabbit

Background This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human FGR
Gene ID 2268
Swiss Prot P09769
Synonyms SRC2; c-fgr; c-src2; p55-Fgr; p58-Fgr; p55c-fgr; p58c-fgr
Reactivity Human
Application WB, ICC/IF
Recommended dilution WB: 1:1000-1:5000
ICC/IF: 1:20-1:50
Calculated MW 60 kDa
Observed MW 60 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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