Product Name :
PGK1 Rabbit pAb
Cat.No.:
db1875
Synonyms :
PGKA; MIG10; HEL-S-68p
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
Conjugation/Formulation:Un-conjugated
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Background
The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome. [provided by RefSeq, Jan 2014]
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Immunogen
A synthetic peptide of human PGK1
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Gene ID
5230
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Swiss Prot
P00558
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Synonyms
PGKA; MIG10; HEL-S-68p
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Reactivity
Human, Mouse, Rat
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Application
WB, ICC/IF, FC
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Recommended dilution
WB: 1:1000
ICC/IF: 1:50
FC: 1:20
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Calculated MW
45 kDa
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Observed MW
45 kDa
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Host species
Rabbit
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Clonality
Polyclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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订购信息
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Package
Price (RMB)
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20μL
598
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50μL
998
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100μL
1798
- 货期:现货
For research use only. Not intended for diagnostic.