GLCNE Rabbit pAb - diagbio | 戴格生物

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GLCNE Rabbit pAb

db1889

Datasheet

Product Name : GLCNE Rabbit pAb

Cat.No.: db1889

Synonyms : NM; DMRV; IBM2; Uae1; GLCNE

Application : WB, ICC/IF, IP

Reactivity : Human, Rat

Host species : Rabbit

Background The protein encoded by this gene is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction. Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of malignant cells. Mutations in this gene are associated with sialuria, autosomal recessive inclusion body myopathy, and Nonaka myopathy. Alternative splicing of this gene results in transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human GLCNE
Gene ID 10020
Swiss Prot Q9Y223
Synonyms NM; DMRV; IBM2; Uae1; GLCNE
Reactivity Human, Rat
Application WB, ICC/IF, IP
Recommended dilution WB: 1:1000-1:5000
ICC/IF: 1:50
IP: 1:20
Calculated MW 79 kDa
Observed MW 75 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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