Phospho-Insulin Receptor (Tyr1185) Rabbit pAb - diagbio | 戴格生物

产品中心 Products Center

您当前的位置：

Phospho-Insulin Receptor (Tyr1185) Rabbit pAb

db20041

年底大促

Datasheet

Product Name : Phospho-Insulin Receptor (Tyr1185) Rabbit pAb

Cat.No.: db20041

Synonyms : HHF5; CD220

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated

Background This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Tyr1185 of human Insulin Receptor
Gene ID 3643
Swiss Prot P06213
Synonyms HHF5; CD220
Reactivity Human
Application WB, ICC/IF, IP
Recommended dilution WB: 1:1000
ICC/IF: 1:50
IP: 1:20
Calculated MW 156 kDa
Observed MW 95 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

订购信息