eIF5A Rabbit pAb - diagbio | 戴格生物

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eIF5A Rabbit pAb

db20081

年底大促

Datasheet

Product Name : eIF5A Rabbit pAb

Cat.No.: db20081

Synonyms : EIF-5A; EIF5A1; eIF5AI

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated

Background mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts.
Immunogen A synthetic peptide of human eIF5A
Gene ID 1984
Swiss Prot P63241
Synonyms EIF-5A; EIF5A1; eIF5AI
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC/IF, FC, IP
Recommended dilution WB: 1:2000
IHC: 1:20
ICC/IF: 1:100
FC: 1:20
IP: 1:20
Calculated MW 17 kDa
Observed MW 17 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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