Angiotensin Converting Enzyme 1 Rabbit pAb
Product Name :
Angiotensin Converting Enzyme 1 Rabbit pAb
Cat.No.:
db20196
Synonyms :
DCP; ACE1; DCP1; CD143
Reactivity :
Human, Mouse
Host species :
Rabbit
Conjugation/Formulation：Un-conjugated
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Background
This gene encodes an enzyme involved in in blood pressure regulation and electrolyte balance. It catalyzes the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. ACE also inactivates the vasodilator protein, bradykinin. Accordingly, the encoded enzyme increases blood pressure and is a drug target of ACE inhibitors, which are often prescribed to reduce blood pressure. This enzyme additionally plays a role in fertility through its ability to cleave and release GPI-anchored proteins in testes. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme. This polymorphism, as well as mutations in this gene, have been implicated in a wide variety of diseases including cardiovascular pathophysiologies, psoriasis, renal disease, stroke, and Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2020]
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Immunogen
A synthetic peptide of human Angiotensin Converting Enzyme 1
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Gene ID
1636
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Swiss Prot
P12821
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Synonyms
DCP; ACE1; DCP1; CD143
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Reactivity
Human, Mouse
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Application
WB, IHC
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Recommended dilution
WB: 1:1000
IHC: 1:50
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Calculated MW
150 kDa
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Observed MW
180 kDa
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Host species
Rabbit
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Clonality
Polyclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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20μL
598
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50μL
998
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100μL
1798
- 货期：现货
For research use only. Not intended for diagnostic.
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