Phospho-Nucleophosmin (Thr199) Rabbit pAb - diagbio | 戴格生物

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Phospho-Nucleophosmin (Thr199) Rabbit pAb

db20218

年底大促

Datasheet

Product Name : Phospho-Nucleophosmin (Thr199) Rabbit pAb

Cat.No.: db20218

Synonyms : B23; NPM

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated

Background The protein encoded by this gene is involved in several cellular processes, including centrosome duplication, protein chaperoning, and cell proliferation. The encoded phosphoprotein shuttles between the nucleolus, nucleus, and cytoplasm, chaperoning ribosomal proteins and core histones from the nucleus to the cytoplasm. This protein is also known to sequester the tumor suppressor ARF in the nucleolus, protecting it from degradation until it is needed. Mutations in this gene are associated with acute myeloid leukemia. Dozens of pseudogenes of this gene have been identified. [provided by RefSeq, Aug 2017]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Thr199 of human Nucleophosmin
Gene ID 4869
Swiss Prot P06748
Synonyms B23; NPM
Reactivity Human
Application WB, IHC, ICC/IF, FC, IP
Recommended dilution WB: 1:2000
IHC: 1:50
ICC/IF: 1:50
FC: 1:20
IP: 1:20
Calculated MW 33 kDa
Observed MW 38 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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