SF3B1 Rabbit pAb - diagbio | 戴格生物

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SF3B1 Rabbit pAb

db20259

年底大促

Datasheet

Product Name : SF3B1 Rabbit pAb

Cat.No.: db20259

Synonyms : MDS; PRP10; Hsh155; PRPF10; SAP155; SF3b155

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated

Background This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human SF3B1
Gene ID 23451
Swiss Prot O75533
Synonyms MDS; PRP10; Hsh155; PRPF10; SAP155; SF3b155
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC/IF, FC
Recommended dilution WB: 1:1000
IHC: 1:50
ICC/IF: 1:50
FC: 1:200
Calculated MW 146 kDa
Observed MW 155 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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