WRN Rabbit pAb - diagbio | 戴格生物

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WRN Rabbit pAb

db2036

年底大促

Product Name : WRN Rabbit pAb

Cat.No.: db2036

Synonyms : Werner's syndrome helicase WRN; DNA helicase, RecQ-like type 3; RecQ protein-like 2; Werner syndrome protein; RECQ3; RECQL2; RECQL3

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated Un-conjugated

Background This gene encodes a member of the RecQ subfamily of DNA helicase proteins. The encoded nuclear protein is important in the maintenance of genome stability and plays a role in DNA repair, replication, transcription and telomere maintenance. This protein contains a N-terminal 3' to 5' exonuclease domain, an ATP-dependent helicase domain and RQC (RecQ helicase conserved region) domain in its central region, and a C-terminal HRDC (helicase RNase D C-terminal) domain and nuclear localization signal. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by accelerated aging and an elevated risk for certain cancers. [provided by RefSeq, Aug 2017]
Immunogen A synthetic peptide of human WRN
Gene ID 7486
Swiss Prot Q14191
Synonyms Werner's syndrome helicase WRN; DNA helicase, RecQ-like type 3; RecQ protein-like 2; Werner syndrome protein; RECQ3; RECQL2; RECQL3
Reactivity Human
Application WB
Recommended dilution WB: 1:1000-1:5000
Calculated MW 163 kDa
Observed MW 200 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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