APLP2 Rabbit pAb - diagbio | 戴格生物

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APLP2 Rabbit pAb

db20407

年底大促

Datasheet

Product Name : APLP2 Rabbit pAb

Cat.No.: db20407

Synonyms : APPH; APPL2; CDEBP; APLP-2

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated

Background This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
Immunogen A synthetic peptide of human APLP2
Gene ID 334
Swiss Prot Q06481
Synonyms APPH; APPL2; CDEBP; APLP-2
Reactivity Human, Mouse, Rat
Application WB, IHC
Recommended dilution WB: 1:2000-1:10000
IHC: 1:50
Calculated MW 87 kDa
Observed MW 115 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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