Phospho-Rb (Ser780) Rabbit pAb
Product Name :
Phospho-Rb (Ser780) Rabbit pAb
Cat.No.:
db20413
Synonyms :
RB; pRb; OSRC; pp110; p105-Rb; PPP1R130; p110-RB1
Reactivity :
Human
Host species :
Rabbit
Conjugation/Formulation：Un-conjugated
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Background
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]
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Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Ser780 of human Rb
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Gene ID
5925
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Swiss Prot
P06400
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Synonyms
RB; pRb; OSRC; pp110; p105-Rb; PPP1R130; p110-RB1
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Reactivity
Human
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Application
WB, IHC
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Recommended dilution
WB: 1:2000
IHC: 1:20
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Calculated MW
106 kDa
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Observed MW
110 kDa
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Host species
Rabbit
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Clonality
Polyclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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20μL
698
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50μL
1398
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100μL
2398
- 货期：现货
For research use only. Not intended for diagnostic.
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