Product Name :
Bag3 Rabbit pAb
Cat.No.:
db2056
Synonyms :
BIS; MFM6; BAG-3; CAIR-1
Reactivity :
Human
Host species :
Rabbit
Conjugation/Formulation:Un-conjugated
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Background
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008]
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Immunogen
A synthetic peptide of human Bag3
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Gene ID
9531
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Swiss Prot
O95817
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Synonyms
BIS; MFM6; BAG-3; CAIR-1
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Reactivity
Human
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Application
WB, IHC, IP
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Recommended dilution
WB: 1:1000-1:5000
IHC: 1:20
IP: 1:20-1:50
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Calculated MW
62 kDa
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Observed MW
74-80 kDa
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Host species
Rabbit
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Clonality
Polyclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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20μL
598
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50μL
998
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100μL
1798
- 货期:现货
For research use only. Not intended for diagnostic.