Phospho-NMDAR2B (Ser1303) Rabbit pAb
Product Name :
Phospho-NMDAR2B (Ser1303) Rabbit pAb
Cat.No.:
db20662
Synonyms :
NR3; MRD6; NR2B; hNR3; EIEE27; GluN2B; NMDAR2B
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
Conjugation/Formulation：Un-conjugated
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Background
This gene encodes a member of the N-methyl-D-aspartate (NMDA) receptor family within the ionotropic glutamate receptor superfamily. The encoded protein is a subunit of the NMDA receptor ion channel which acts as an agonist binding site for glutamate. The NMDA receptors mediate a slow calcium-permeable component of excitatory synaptic transmission in the central nervous system. The NMDA receptors are heterotetramers of seven genetically encoded, differentially expressed subunits including NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The early expression of this gene in development suggests a role in brain development, circuit formation, synaptic plasticity, and cellular migration and differentiation. Naturally occurring mutations within this gene are associated with neurodevelopmental disorders including autism spectrum disorder, attention deficit hyperactivity disorder, epilepsy, and schizophrenia. [provided by RefSeq, Aug 2017]
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Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Ser1303 of human NMDAR2B
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Gene ID
2904
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Swiss Prot
Q13224
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Synonyms
NR3; MRD6; NR2B; hNR3; EIEE27; GluN2B; NMDAR2B
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Reactivity
Human, Mouse, Rat
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Application
WB, ICC/IF
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Recommended dilution
WB: 1:1000
ICC/IF: 1:20
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Calculated MW
166 kDa
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Observed MW
200 kDa
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Host species
Rabbit
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Clonality
Polyclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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20μL
698
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50μL
1398
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100μL
2398
- 货期：现货
For research use only. Not intended for diagnostic.
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