Product Name :
APC Rabbit pAb
Cat.No.:
db20693
Synonyms :
GS; DP2; DP3; BTPS2; DESMD; DP2.5; PPP1R46
Reactivity :
Human, Rat
Host species :
Rabbit
Conjugation/Formulation：Un-conjugated
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Background
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Mutations in the APC gene have been found to occur in most colorectal cancers. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Dec 2019]
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Immunogen
A synthetic peptide of human APC
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Gene ID
324
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Swiss Prot
P25054
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Synonyms
GS; DP2; DP3; BTPS2; DESMD; DP2.5; PPP1R46
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Reactivity
Human, Rat
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Application
WB, IHC, ICC/IF, FC, IP
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Recommended dilution
WB: 1:1000
IHC: 1:20
ICC/IF: 1:20
FC: 1:20
IP: 1:20
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Calculated MW
312 kDa
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Observed MW
160 kDa
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Host species
Rabbit
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Clonality
Polyclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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20μL
598
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50μL
998
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100μL
1798
- 货期：现货
For research use only. Not intended for diagnostic.
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