GRID2 Rabbit pAb - diagbio | 戴格生物

产品中心 Products Center

您当前的位置：

GRID2 Rabbit pAb

db21140

年底大促

Datasheet

Product Name : GRID2 Rabbit pAb

Cat.No.: db21140

Synonyms : GluD2; SCAR18

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated

Background The protein encoded by this gene is a member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. The encoded protein is a multi-pass membrane protein that is expressed selectively in cerebellar Purkinje cells. A point mutation in the mouse ortholog, associated with the phenotype named 'lurcher', in the heterozygous state leads to ataxia resulting from selective, cell-autonomous apoptosis of cerebellar Purkinje cells during postnatal development. Mice homozygous for this mutation die shortly after birth from massive loss of mid- and hindbrain neurons during late embryogenesis. This protein also plays a role in synapse organization between parallel fibers and Purkinje cells. Alternate splicing results in multiple transcript variants encoding distinct isoforms. Mutations in this gene cause cerebellar ataxia in humans. [provided by RefSeq, Apr 2014]
Immunogen A synthetic peptide of human GRID2
Gene ID 2895
Swiss Prot O43424
Synonyms GluD2; SCAR18
Reactivity Human, Mouse, Rat
Application WB
Recommended dilution WB: 1:2000
Calculated MW 113 kDa
Observed MW 113 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

订购信息